Breast cancer is the second largest in Indonesia. Number of breast cancer is increasing from year to year. According to WHO, more than 70% of breast cancer deaths occur in developing countries, meanwhile, have not found a specific treatment for breast cancer. In Indonesia, there has been a tremendous surge of breast cancer cases in the last 10 years, breast cancer ranked as the leading cause of death rose from rank 12 to rank 6th. The incidence of breast cancer in Indonesia is estimated at 180 per 100,000 population. Data Hospital Information System (SIRS) 2004-2007 showed that the incidence of breast cancer is a type of cancer is highest in Indonesia.
Moreover, the incidence of breast cancer in Indonesia increased by 60% from 2004 to 2007. According to some reports, breast cancer rates are estimated at 20% of all cancers in women, the incidence of about 100 people with 100,000 inhabitants per year, and the mortality was about 11, 22% of all cancer incidence. Based on data from Cancer Register, Sub Directorate of Cancer 2007, breast cancer (32%) is the highest in 31 types of cancer hospitals in Jakarta. Breast cancer patients in Indonesia there are only 18 years old (Suryaningsih and Bertiana, 2009). In addition to a number of cases, more than 70% of patients with breast cancer is found at an advanced stage (Moningkey, 2000). Data from the Directorate General of Medical Services of the Ministry of Health showed improvement in 1992-1993, from 3.9 to 7.8 (Ambarsari, 1998).
Chemotherapy is a cancer treatment that is most common, but the method tesebut side effects for the patient. Hard drugs customized prescription was offered to the patient in an attempt to cure the disease. But apparently, the drugs offered are often lead to other negative effects to the body. Pearl grass (Hedyotis corymbosa) has great potential for a wide range of alternative treatments. Pearl grass oleanoat acid and Ursolic acid can inhibit cancer cells. In addition, the content of flavonoid glycosides in pearl grass is able to inhibit the process of carcinogenesis. Pearl grass has great benefits as anticancer agents for the lives of the people who always consume instant foods are carcinogenic. However, the shape and feels foreign to the people will make them less interested in taking it. Therefore, given the benefits earlier, then grass pearls can be processed into pudding a healthy alternative to breast cancer prevention.
Pearl grass (Hedyotis corymbosa)
Pearl grass or Hedyotis corymbossa included in the genus Rubiacae. Pearl grass weed is a plant commonly grown in moist soil and enough sunlight, such as on the street, at the edge of the gutter or on the rice fields (Febia et al., 2005). Pearl grass and soft-sided stems, leaves are small and line of sight intersects with short leaf stalks. The flowers are 2-5 compound interest, shaped like a white umbrella, pieces whose edges broken and reproduce by seeds (Sopandi, 2006).
According Febriansah et al. (2012), pearl grass classification is as follows:
- Division: Spermatophyta
- Sub Division: Angiospermae
- Class: Dicotyledoneae
- Order: Rubiales
- Family: Rubiaceae
- Genus: Hedyotis
- Species: Hedyotis corymbosa L
Here is a picture pearl grass (Hedyotis corymbosa) taken by Amelia (2006).
Figure 1. Grass Pearls (Hedyotis corymbosa)
All parts of the plant can be used as a drug that is believed efficacious as anti-inflammatory, anticancer, antipyretic, diuresis, blood circulation, antitoxin, and many more (Hariya, 2004). Society consume in the form of cooking water plants, or plants that are crushed and processed (in the form of tablet, granule, tea, and capsules) in a variable dose (Sudarsono, 2002). Hedyotis corymbosa contain various chemical compounds, namely acid Ursolic, oleanolat acid, γ-sitosterol, β-sitosterol, stigmasterol, compound iridoid (asperulosid, skandosidmetilester, benzoilskandosidmetilester), n-benzoyl-1-phenylalanine-1-fenilalaninol acetate, flavonoids, hentriacontan , p-kumarat acid, tannins, and coumarin (Hariya, 2004). Various chemical compounds have properties that vary with different effects in the body.
This journal article can explain more: Clinical Pearls in Breast Disease
Utilization of Grass Pearls (Hedyotis corymbosa)
Utilization of the direct consumption as raw material Mutiara grass (Hedyotis corymbosa) is a rare thing done by the community. Therefore, the utilization requires appropriate preparations so that people can consume these beneficial ingredients in a reasonable and controlled with the recommended dose. The pudding is processed materials agar-agar and other mixed materials. Here are the methods used in processing the Pearl Grass (Hedyotis corymbosa) into a simple fresh custard using a mixture of gelatin without taste useful as a breast cancer preventive agents for human life.
The materials used to make pudding pearl grass are as follows:
• jello without flavor 1 package
• Low Sugar calories 50 grams
• Water 400 ml
• Milk white powder 50 grams
• Egg yolks 2 eggs
• flour 4 tablespoons cornstarch
• Chocolate Flavor 50 grams
• Grass pearl 100 grams
The tools used to make pudding pearl grass are as follows:
• Gas stove
• scoop
• Pan
• Traditional pounder
• Sieve
• Plastic
• Petersham
• Tablespoon
• bowls
• Pudding mold
• Refrigerator
Procedures to make pudding pearl grass are as follows:
•
First of all, the tools and materials to be used
is prepared.
•
Grass pearls cleaned by washing with water until
clean.
•
Water boil, then pearl grass put in water that
has been boiling.
•
Once boiled, drained pearl grass and put into a
blender.
•
Grass pearl blender until smooth and ready to
put into the pudding mixture.
•
After a smooth, manufacture pudding mixture
begins to boil 400 ml of water over low heat.
•
After that, 1 packet of jelly incorporated and
stirring until blended.
•
Then, 50 grams of low-calorie sugar incorporated
and stirred again.
•
While gelatin is being cooked, stirring
constantly, pudding mixture prepared by mixing 2 egg yolks with 4 tablespoons
of cornstarch.
•
To add flavor, 50 grams of milk powder mixed
into pudding mixture and stirred again until blended.
•
After that, 50 grams of cocoa powder mixed into
the dough.
•
Then mix eggs and cornstarch mixed into the
gelatin mixture and stir until boiling.
•
Once the dough boiling, pearl grass timbukkan
inserted into the pudding mixture and stir briefly until blended.
•
Once blended, the stove is turned off and prints
of pudding prepared.
•
The batter pudding dituangkann into prints of
and allowed to stand until cold custard and lost steam heat.
•
Once the dough is cold custard, pudding put in
the refrigerator.
•
After 20 minutes, pudding ready to serve.
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